Opposing that evidence, some authors did not find changes in circulatory relaxin-2 levels in patients with CHF (Table 2) or in the severity of the disease [100], were unable to confirm if relaxin-2 could predict HF readmission or death over the following year, and also reported no correlation between relaxin-2 and N-terminal (NT)-proBNP, a strong prognostic marker of HF [97]. Here, NPPB is linked to congestive heart failure.