A clinical study identified that oxidative stress marker, including increased advanced oxidation protein product, myeloperoxidase, malondialdehyde, nitric oxide, oxidized low-density lipoprotein, and decreased glutathione, are closely related to the carotid atherosclerosis process in patients with CKD, indicating those oxidative markers may serve as the markers to predict the progression of CKD [34]. This evidence concerns the gene MPO and chronic kidney disease.