The viral oncoprotein E7, which belongs to the human papillomavirus responsible for causing cervical cancer as well as genital cancers such as vulvar, vaginal, anal and penile cancers [267], interferes with FOXM1 sumoylation, protecting FOXM1 from degradation [265], which increases cell proliferation [266]. The gene discussed is FOXM1; the disease is cervical carcinoma.