For example, research conducted by Suelves and colleagues [62] examined the consequences of BDNF/TrkB/p75NTR imbalance in a Huntington’s disease (HD) mouse model, showing that the reduction of BDNF and TrkB levels, along with an increase in p75NTR expression, correlated with striatal neuropathology and motor dysfunction. Here, NTRK2 is linked to Huntington disease.