Significantly, 26 risk variants for schizophrenia were located in 31 hmsLRI-E regions and most of them were connected with different genes previously proposed to contribute to the pathology (TRIM8, SREBF2, LINC00461, ETF1, CTNND1, PITPNM2, TCF4, FOXP1, NSD3, Table 3 and Table S2 for details). The gene discussed is TRIM8; the disease is schizophrenia.