These pathways are important in cell migration, a key neurodevelopmental process altered in many NDD, including ASD and SCZ [46]; as the disruption of the enhancer–promoter connectivity caused by CNVs presumably leads to a transcriptional deregulation of TRIO, the entire canonical cell migration pathway might be affected, hence providing a link between the CNVs and the NDD phenotype observed. Here, TRIO is linked to Neurodevelopmental delay.