When combined with TNF-related apoptosis-inducing ligand (TRAIL), Au NPs augmented the anti-tumor effects of TRAIL in female BALB/c mice subcutaneously injected with non-small-cell lung cancer (NSCLC) cells and increased mitochondrial fragmentation and fission in NSCLC cells through increasing the recruitment of Drp1 protein to the mitochondria [246]. This evidence concerns the gene DNM1L and non-small cell lung carcinoma.