Mutations in genes encoding the alpha and beta subunits of the potassium channels conducting these currents lead to several arrhythmic disorders, such as Long QT syndrome (LQTS), Short QT syndrome (SQTS), familial atrial fibrillation (FAF), Brugada syndrome (BrS), and early repolarization syndrome (ERS), and can also be found in cardiac sudden death (SCD) victims (OMIM). Here, KCNA3 is linked to Familial short QT syndrome.