Growing evidence shows that transforming growth factor-beta 1 (TGF-β1) is the critical fibrogenic factor in IPF, increasing its expression, promoting alveolar epithelial cells apoptosis, and facilitating epithelial-mesenchymal transition (EMT), which contributes to myofibroblasts expansion from epithelial cells [7]; and its persistence in lung tissue is associated with chronic and progressive fibrosis [8]. Here, TGFB1 is linked to idiopathic pulmonary fibrosis.