Mφ were stimulated with LPS or IL-4 to induce M1 or M2 polarization, then untreated Mφ and M2 were concomitantly exposed to tumoral conditioned medium (TCM) from hormone-responsive MCF-7 (epithelial model of metastatic adenocarcinoma of BC) or triple-negative MDA-MB-231 BC cell lines for in vitro TAMs induction [21]. The gene discussed is IL4; the disease is breast cancer.