Additionally, recent AD GWAS has nominated many microglial-specific risk genes, including CD11b (integrin alpha M, ITGAM, or αM) and CD11c (integrin alpha X, ITGAX, or αX), which are integrins responsible for phagocytosis mediated by complement system and the recruitment and migration of monocytes [4]. The gene discussed is ITGAM; the disease is Alzheimer disease.