Analysis of the expression level of CYP27C1 in different human lung cancer cell lines showed that the mRNA level of CYP27C1 was significantly higher in A549 (p = 0.0276) and H1975 (p = 0.0007), and relatively lower in H460 (p = 0.0014), compared to that in BEAS-2B cells (Figure 1A). This evidence concerns the gene CYP27C1 and lung cancer.