Given that the expression level of some CYP450 family members can influence certain cellular activities involved in cell proliferation and drug sensitivity, we detected and compared the sensitivity of four anticancer agents, including one approved drug for non-small cell lung cancer treatment (vinorelbine), and three protein kinase inhibitors (picropodophyllin, pacritinib, and SKLB610) in four human lung cancer cell lines (Supplementary Figure S4). This evidence concerns the gene WEE1 and lung cancer.