CD274 and neoplasm: Since Bas tumors show high immune cell infiltration, including high levels of tumor-associated immune cells (mostly CD8+ T lymphocytes with higher inhibitory molecular expression) and tumor-associated neutrophils [21,27,52,53], and are enriched with CD274(PD-L1)-positive tumor cells, they could be good candidates to immunotherapy [10,13,21,42,54,55,56].