PEVs in SS and vasculitis express many pro-inflammatory and pro-coagulant proteins, including TF, IgG, sialic acid-binding immunoglobulin-type lectin 11 (siglec-11), tumor necrosis factor receptor superfamily member 19L (RELT), Nectin 1 and 4, TFN RII, IL1-R4, junctional adhesion molecule B (JAM-B), Cadherin-11, 13 and P-cadherin, glypican 5, thrombospondin 2 and 5, CD23, granulocyte colony-stimulating factor (G-CSF), angiotensinogen, UL16-binding protein 1 and 2 (ULBP-1 and 2), interstitial collagenase (MMP-1), CD229, CD84, CD58, and IL-12p40 [147,151,160,164]. Here, CSF3 is linked to vasculitis.