Human astrocytoma cell SGs contain mRNAs that are known to be involved in glioma signaling and the mammalian target of rapamycin pathway, involving proteins such as the cytokinetic proteins epithelial cell transforming 2 and Aurora kinase B (AURKB) together with canonical components of SGs, such as TIAR and G3BP1 [127]. The gene discussed is TIAL1; the disease is central nervous system cancer.