Western blotting revealed that expression levels of α-SMA, β- ENaC, full-length γ-ENaC, and cleaved γ-ENaC, but not MR expression, were decreased in IRI/Aldo + AML rats, compared with the levels in IRI/Aldo rats, while the expression of α-ENaC did not differ among the four groups (Figure 7D). This evidence concerns the gene ACTA1 and acute myeloid leukemia.