GRM1 and acute myeloid leukemia: Of the 157 genes, 27 were included in the eight pathways described above: 18 genes (IL1B, SUCNR1, MUC1, PLXNB1, IFNB1, OR1L4, MUC16, OR1Q1, GRM1, OR1L8, RAMP1, IFNW1, OR1J1, IL5RA, OR13C4, GDF6, GNG8 and RTP3) were upregulated while nine genes (OR5B12, CLEC10A, CCR5, PDGFA, WNT10A, DAGLA, TNFSF15, TNFRSF11A, and CSF1R) were downregulated in the PD-AML group, compared with the PND-AML group (Figure 1).