One molecular signaling pathway responsible of thyroid cancer is the overexpression of FOXA1–a transcription factor of the Forkhead box (FOX) protein family, and a pioneer factor that facilitates oncogenic transcription factors; its hyperreactive signaling due to gene amplification or overexpression was reported in many cases of thyroid lesions and tumors [123]. This evidence concerns the gene FOXA1 and thyroid gland carcinoma.