ABCB1 and lung carcinoma: AA was tested by Cheng et al. [57] as an MDR modulator in MDR1- overexpressing cisplatin (DDP)-resistant A549/DDP lung cancer cells where the phytocompound significantly increased the cytotoxicity of cisplatin against cisplatin-resistant cells without having any impact on the cisplatin treatment of chemosensitive A549 cells.