In a similar manner as with lung cancer, AA down-regulated the expression of epithelial–mesenchymal transition markers in a dose-dependent manner; collectively, AA induced the apoptosis of colon cancer cells and prevented their migration by regulating the expression of Pdcd4 through the PI3K/Akt/mTOR/p70S6K signaling pathway (Figure 5). The gene discussed is AKT1; the disease is colonic neoplasm.