VDAC1 and neoplasm: Subsequently, in order to investigate whether—as happens in tumor cells [111]—HK-1 interacts with VDAC1 at the MOM, we also conducted coimmunoprecipitation studies by using an anti-HK-1 polyclonal antibody as bait antibody, followed by immunoblotting with a monoclonal antibody that specifically interacts with VDAC1.