Common features of patients P6, P7 and P10 in this second group were many microdeletions at 7q, 9p, 16p, 17q, and 20q in the genome of adenoma tissue compared to that of adjacent tissue, and likewise without the presence of MALAT1 or TALAM1 gain on chromosome 11 or any other gain. The gene discussed is MALAT1; the disease is adenoma.