EGF is also involved in the regulation of prostate growth and function, and its expression is increased in early and localized PCa; however, in our study, we observed a decrease in its levels in the urine of PCa2 animals and in animals with score 2 lesions, which may be explained by the stage of prostate carcinogenesis [31,32]. The gene discussed is EGF; the disease is posterior cortical atrophy.