The individual studies using dengue ICT for dengue NS1 only (Pooled SN = 70.97%, SP = 94.73%), IgM only (Pooled SN = 40.32%, SP = 93.01%), and combined NS1/IgM (Pooled SN = 78.62%, SP = 88.47%) detection in acute studies were pooled and analyzed separately, as discussed in subsequent sections. Here, CD40LG is linked to dengue disease.