A total of (5/13) 38.4% of BC patients harboured PVs in genes with moderate-to-high risk for BC, including PALB2 (c.1451T>G), TP53 (c.451C>G and c.376-1G>A), ATM (c.6100C>T) and CHEK2 (c.846+1G>C). The gene discussed is PALB2; the disease is breast cancer.