BRCA1 and breast cancer: Among the BC patients, 8/13 (61.5%) VPs were in the BRCA1/2 genes, whereas 5/13 (38.4%) were in other high- and moderate-risk genes, including PALB2 (c.1551T>G), TP53 (c.451C>G and c.376-1G>A), ATM (c.6100C>T) and CHEK2 (c.846+1G>C).