In Figure 5A, the DEGs were enriched in 12 GO terms, including 4 BP terms (p53 signaling pathway and melanoma), 4 CC terms (signal recognition particle and platelet α granule), and 4 KEGG pathways (negative regulation of defense response and the establishment of protein localization to the endoplasmic reticulum; Figure 5A and Supplementary Table S5). This evidence concerns the gene TP53 and melanoma.