In this sense, ASD and HSD share several clinical manifestations in adulthood [45], including proprioceptive impairment (three out of five patients in our study) and autonomic dysfunction (four out of five in our research), highlighting the theoretical involvement of ZNF717 as a potential etiological factor behind the association between ASD and HSD in the adult population. The gene discussed is ZNF717; the disease is Abnormal autonomic nervous system physiology.