For the AGTR1 and AGT pair for the HOM2-HET model (the presence of the homozygous AA genotype of the AGTR1 gene and the heterozygous AG genotype of the AGT gene), we have demonstrated a 2.82-fold higher risk of HF (OR = 2.82, 95% CI 1.32–6.26, p = 0.042). Here, AGTR1 is linked to hydrops fetalis.