For the A1066C AGTR1 polymorphism under the dominant model, the carriers of the C allele (A/C-C/C) had a reduced risk of HF (OR = 0.54, 95% CI 0.029–0.97, p = 0.039), and finally for the overdominant model, A/C heterozygotes occurred less frequently than A/A–C/C homozygotes, which conferred a lower risk of HF (OR = 0.47, 95% CI 0.25–0.87, p = 0.016) (Table 2). This evidence concerns the gene AGTR1 and hydrops fetalis.