Indeed, quite a lot of studies reported direct or indirect targeting of EGR1 by miR-203a, miR-377-3p, miR-125b-2-3p and miR-301b in many cancer cell lines, which slowed down the proliferation of cancer cells to a certain extent by inhibiting the expression of EGR1 [32,33,34,35]. The gene discussed is EGR1; the disease is cancer.