Through the enrichment analysis of DCCGs, it was found that AMI disease is significantly related to the positive regulation of vascular-related smooth muscle cell proliferation, and HBEGF, THBS1, NR4A3, NLRP3, EDN1, and MMP9, which are involved in this function, are significantly related to AMI/MI in DISEASES and the literature. Here, MMP9 is linked to myocardial infarction.