ANGPTL8 and obesity due to melanocortin 4 receptor deficiency: Apart from levels of obesity traits (weight, BMI and WC), participants in our study cohort afflicted with obesity differed significantly from those without obesity in the levels of body composition traits (PBF: percentage body fat), lipid traits (TG), glycemic traits (FPG and HbA1c), angiopoietin-like proteins (ANGPTL3, ANGPTL4, and ANGPTL8), and diabetes status (Table 1).