TREX1 and Aicardi-Goutieres syndrome 1: There are four heritable TREX1-related disorders [26]: Aicardi–Goutières Syndrome type 1 (AGS1—OMIM #225750), Familial Chilblain Lupus (FCL—OMIM #610448), Systemic Lupus Erythematosus (SLE—OMIM #152700), and Retinal Vasculopathy with Cerebral Leukodystrophy (RVCL—OMIM #192315).