It was revealed that TP63 (transformation-related protein 63), VHL (von Hippel-Lindau tumor suppressor, LEF1 (Lymphoid enhancer-binding factor 1), RUNX3 (Runt-related transcription factor 3), ESR1 (Estrogen receptor 1), EGR1 (Early growth response protein 1) and AR (Androgen receptor) possibly played significant roles in NSCLC. Here, LEF1 is linked to non-small cell lung carcinoma.