ARID1A and Coffin-Siris syndrome: ARID1A encodes a member of the SWItch/Sucrose NonFermenting (SWI/SNF) complex; variants in genes encoding the components of the SWI/SNF complex result in Coffin-Siris syndrome, a syndromic form of intellectual disability frequently associated with agenesis or hypoplasia of the corpus callosum [14,15].