HDAC1 and cancer: These proteins are directly associated with cancer progression and are reported to interact as well; for instance, RBM45 acts competitively to histone deacetylase 1 (HDAC1) for binding to FUS as a DNA damage response, while SRSF9 and HNRPF are implicated in signaling and EMT regulation, since they modulate tumorigenesis through the WNT signaling pathway and EMT through SNAIL1 stabilization, respectively [61,62,63].