According to The Intersectoral Coordination Mechanism for the Control of Antimicrobial Resistance (ISKRA) guidelines for treatment of prostatitis, the first line of treatment of acute bacterial prostatitis are parenteral third generation cephalosporins ± aminoglycosides or aminopenicillins + beta-lactamase inhibitors or ureidopenicillins + beta-lactamase inhibitors or fluoroquinolones (ciprofloxacin, levofloxacin) for 7 to 10 days, followed by oral fluoroquinolones for a further 2 to 4 weeks. This evidence concerns the gene LACTB and male reproductive organ cancer.