Induction of the apoptosis biomarker p53 is reported to induce liver and cardiac fibrosis [12,13], in addition to the biomarker of profibrogenesis, a tissue inhibitor of metalloproteinases-1 (TIMP-1) that promotes liver fibrosis via the inhibition of the antifibrotic metalloproteinases upon the activation of HSCs [14]. This evidence concerns the gene TIMP1 and Hepatic fibrosis.