After Perl’s stain, when RS is observed in at least 15% of erythroblasts (or in at least 5% in case of SF3B1 mutation), the diagnosis of myelodysplastic neoplasms with ring sideroblasts (MDS-RS) according to the 2016 revised WHO classification was retained [7]. Here, SF3B1 is linked to myelodysplastic syndrome.