SV2A and supranuclear palsy, progressive, 1: In a recent study conducted on 15 CBS patients and 14 PSP patients who were examined using [11C]C-UCB-J and a synaptic vesicle glycoprotein 2A radiotracer, reduced accumulation was found in the frontal, temporal, parietal, and occipital lobes; in the cingulate cortex, the hippocampus, the insular cortex, and the amygdala; and in the subcortical structures.