FOLH1 and neoplasm: Concordance between MRI and PET with PSMA-targeting radiopharmaceuticals was high for patient-wise and lesion-wise detection in recurrent HGG: uptake of PSMA-targeting radiopharmaceuticals was found precisely in the tumor regions that showed contrast enhancement on MRI, suggesting that blood-brain barrier (BBB) damage could be a common factor influencing both contrast enhancement on MRI and PSMA-targeting radiopharmaceutical uptake on PET [20,21].