MiR-206 prevents the suppression of tumor angiogenesis, both in vivo and in vitro, by inhibiting the 14-3-3z/STAT3/HIF-1α/VEGF signaling pathway [252] and preventing normal fibroblast to cancer-associated fibroblast conversion by downregulating VEGFA expression [253]. The gene discussed is VEGFA; the disease is neoplasm.