AKT1 and mycosis fungoides: Those genes are involved in different pathways such as epigenetic and/or chromatin regulation, TCR and T-cell/ cytokine signalling, Jak/signal transducer and activator of transcription (STAT), and phosphoinositide 3-kinases (PI3K)/protein kinase B (Akt) and NF-kB pathway, configuring that a complex mutational landascape may be related to MF/SS pathogenesis [27,29,30].