AQP5 and metastatic malignant neoplasm in the lymph nodes: In addition to the above-mentioned statement, a study by Moosavi [110] found that overexpression of AQP1, AQP3, and AQP5 is inextricably linked to carcinogenesis, metastasis, decreased survival rate, lymph node metastasis, a worse prognosis, and cellular migration and that furthermore, cancer therapies associated with these markers suggest AQP decreases during treatment.