In a previous study, supplementation of fermented rice bran decreased TNF-α, IL-6, and IL-1β levels, thereby increasing body weight and fecal concentration, and reducing intestinal bleeding caused by increased short-chain fatty acids (SCFA) and trypamine to protect the C57BL/6N mice from ulcerative colitis [48], consistent with this study. The gene discussed is IL1B; the disease is ulcerative colitis.