Transactive response-DNA binding protein 43 (TDP-43), has been found in stress granules of patients with frontotemporal dementia and amyotrophic lateral sclerosis, and now it was shown that TDP-43 forms oligomeric assemblies that associate with AβOs and TauOs, suggesting co-partnerships in the pathogeneses of neurodegenerative diseases [58]. The gene discussed is TARDBP; the disease is neurodegenerative disease.