GREM1 and cancer: Notably, among the genes downregulated upon DSCAM-AS1 knockdown were several proliferation activators of endometrial (and other) cancer cells, like NOTCH1 [52,53], HMGA2 [54], PTK2/FAK [55,56], FOSL1 [57], GREM1 [58] and EGR1 [59].