The tumor necrosis factor (ligand) superfamily, member 10 (TNFSF10) (TRAIL), upregulated 7.92-fold in HEC-1B cells with low DSCAM-AS1 levels, cells, has been reported to preferentially induce apoptosis or necroptosis in transformed and tumor cells and to decrease cancer cell growth [60]. The gene discussed is TNFSF10; the disease is cancer.