TRBV25-1 and cancer: Importantly, the strongest correlation coefficient was found when comparing gene expression patterns of TRAV10 and TRBV25-1 genes together (iNKT cell signature) with the M1 signature transcripts in the tumor tissue (R = 0.79), which was higher than total T cells (CD3) and M1 signature (R = 0.68), emphasizing the relevance of iNKT cells and M1-like macrophages proximity in cancer.