IL22 and colitis: The optimal activation of STAT5 is required for IL-22 production in group 3 innate lymphoid cells (ILC3) in colitis, which is critical for the homeostatic maintenance of gut epithelial integrity during Citrobacter rodentium-mediated colitis-induced intestinal disease, suggesting the potential importance of STAT5 in other idiopathic forms of colitis, such as IBD [81].