ALB and diabetes mellitus: As shown in Table 2, diabetes caused a sharp increase in proteinuria (urine albumin mg/24 h), ketonuria, urine specific gravity, blood urea and creatinine, which was significantly (p ≤ 0.0036) ameliorated by metformin to levels still significant (p ≤ 0.0225) to the control group for specific gravity and creatinine.