Furthermore, Yu et al. suggest that the lncRNA kcnq1ot1 plays a role in atherosclerosis and found that the overexpression of kcnq10t1 caused a decrease in the expression of ATP binding cassette transporter A1 (ABCA1), a transmembrane protein that mediates the efflux of cholesterol in macrophages and miR-452-3p [89]. This evidence concerns the gene ABCA1 and atherosclerosis.