ESR1 and leiomyoma: In both tissues, downregulation of PGRB (2.5-fold p < 0.001, 3-fold p < 0.05 for myometrium and leiomyoma, respectively) and ESR1 mRNA (9-fold p < 0.001, 3-fold p < 0.01, for myometrium and leiomyoma, respectively) was observed when compared to T0.