SHBG and polycystic ovary syndrome: While total testosterone (TT) did not differ between the two groups (22.0 ± 13.8 vs. 24.4 ± 3.3 ng/dL; p = 0.2508), free T (FT) was significantly lower in HH-PCOS patients (1.1 ± 1.0 pg/mL vs. 1.7 ± 0.3 pg/mL); p = 0.0003) and SHBG was significantly higher (115.1 ± 51.1 vs. 63.5 ± 33.6 nmol/mL, p < 0.0001), further supporting the observation of lower T in women with HH-PCOS.