Compared with patients whose condition improved/stabilized, those whose disease progressed/who died from ILD were characterized by greater inflammatory activity (mean (SD) DAS28-ESR, 4.4 (1.6) vs. 3.0 (1.2) mg/L; p = 0.012) and higher CRP (median (IQR), 20.0 (6.1–32.0) vs. 6.7 (5.0–13.1) mg/L; p = 0.015). This evidence concerns the gene CRP and interstitial lung disease.